MissMunch

Monday, 12 March 2007

WOOHOOOHOOOO.......... (*trails off*)
I finally found a reason to watch more of Japanese Dramas!
Wooohooohoooooo..
I learn alot from those dramas ok!
It's not the normal sarang heyo kinda mushy stuff only ok!

I learnt a new blood type.
Not A, not B and not O..
BUT..
But..

BOMBAY TYPE!
= )
I roughly know what is it about but i tried to search for it online and there are all chunks of words and medical terms which made me an engineering(ecc) student go gaga.
Where i learnt about it from? I was watching a Kindaichi Special starring Kame as Kindaichi. Got kame, so must watch. LOL! And they mentioned about Bombay blood type. Super rare and they can only get blood transfusion from Bombay blood type people or it will be fatal.
And bits and pieces of what i have read taught me that most Bombay group people are categorized under the O blood group.

I found a chunk of words which seems more summarised online at Yahoo! answers.
A rare genotype (blood group) of people was detected in Mumbai, a few decades back, who neither had A, AB, B or O group of blood. This rare genotype was labelled as the Bombay Blood Group. If a Bombay Blood Group recipient is not transfused the blood of the same group he can die of a haemolytic transfusion reaction occurring as a result of immediate red cell lysis because of the presence of anti H antibodies in the serum of Bombay Blood Group patients. Studies reveal that this is due to the absence of the H substance (antigen) in the red cells. The absence of the H substance is attributed to the deficiency of the enzyme fucosyl transferase. The Bombay Blood Group phenotypes lack H antigen in the red cells and have anti-H in the serum.

Family studies have shown that the Bombay phenotype, called as Oh, is due to the presence in homozygous state of a rare recessive gene. The precursor protein from which the blood group proteins are formed is termed as the H substance. This is bio-chemically produced.

More about it:
Experts say that if proper blood grouping or testing practices is not followed, it can lead to people with Bombay blood group not being detected. According to Dr Mukesh Desai, during cell grouping or routine grouping, Bombay Blood Group would be categorised as O group because they wouldn’t show any reaction to anti-A and anti-B antibodies just like a normal O group. When a cross matching with different blood bags of O group is done, then it would show cross-reactivity or incompatibility. Therefore reverse grouping or Serum grouping has to be performed to detect the Bombay Blood group.

Other issues related to Bombay Blood Group are that blood is incompatible with all A, B and O donors. In routine forward grouping, this blood group would give reaction as an ’O’ blood group where as in serum grouping it would show reaction with ’O’ cells due to the presence of anti H in their serum. Once detected, are registered at Institute of Immuno-haematology (IIH)) for further studies as well as for availability of information regarding the donors of this group.

Since Bombay Blood Group is the rarest of the rare group; it is desirable to develop cryopreservation facilities for rare donor units. Every blood bank can easily maintain a rare blood type donor file from amongst their regular voluntary donors. If the blood banks can borrow or exchange rare blood units in times of need, lot of problems related to rare blood groups like Bombay Blood Group can be solved. This is only possible if each blood bank has a large number of committed regular voluntary donors.
It's quite interesting. Being the frog that i am, i always thought that there are only A, B , C O. I didn't know that some can be tested without them. And that BomBay blood group existed.
And fine, bombay is actually OH? Or O positive. Yahoo! Answers don't give me a definite answer! Some said that it's OH and is OH O+?
And further reading on, Bombay group are tested to have A, B genes but are tested as O.
Confusing. I LOVE J drama more than anything!
Ar! Top Japanese Guys? MatsuJun Koike Kame Yamapi and and and..did i miss anyone out?
Lols. I simply love J drama. Any recommendations??? Hahas!!

Click here for a link on Bombay bloodgroup if you are interested.

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